While this is also a worry, I would choose to be wary of this study as research was conducted on just one pregnant woman who had a severe allergic reaction to a multivitamin administered via IV. While doctors identified Polysorbate 80 as the cause, no other incidences of this type of reaction have been reported.
A recent study has shown a real connection between ingesting Polysorbate 80 and the development of bowel problems – it could be a real worry for those with a predisposition to Colitis.
Relatively low concentrations of two commonly used emulsifiers, namely carboxymethylcellulose and polysorbate-80, induced low-grade inflammation and obesity/metabolic syndrome in wild-type hosts and promoted robust colitis in mice predisposed to this disorder….These results support the emerging concept that perturbed host–microbiota interactions resulting in low-grade inflammation can promote adiposity and its associated metabolic effects. Moreover, they suggest that the broad use of emulsifying agents might be contributing to an increased societal incidence of obesity/metabolic syndrome and other chronic inflammatory diseases.
In a similar vein, the study linked here connected Polysorbate 80 to exacerbated Crohn’s Disease.
Crohn’s disease is common in developed nations where the typical diet is low in fibre and high in processed food. Primary lesions overlie Peyer’s patches and colonic lymphoid follicles where bacterial invasion through M-cells occurs. We have assessed the effect of soluble non-starch polysaccharide (NSP) and food emulsifiers on translocation of Escherichia coli across M-cells.
Translocation of E coli across M-cells is reduced by soluble plant fibres, particularly plantain and broccoli, but increased by the emulsifier Polysorbate-80. These effects occur at relevant concentrations and may contribute to the impact of dietary factors on Crohn’s disease pathogenesis.
Polysorbate 80 has also been causally linked with an increased risk of blood clots, stroke, heart attack, heart failure, and of tumor growth or recurrence in patients with certain types of cancer .
The evidence suggests that this ingredient is potentially toxic, particularly the lower grade versions – which are typically used in cosmetics which list Polysorbate 80 in their ingredients lists.
It can be considered a concern to accept vaccines which contain the ingredient.
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